Rational Design of Peptide Modulators Bi-Directionally Tuning Cav1.3 Channels
نویسندگان
چکیده
منابع مشابه
Bi-directionally controlled thyristors
for a better worldTM The bi-directional controlled thyristor (BCT) is a concept for high power phase control thyristors (PCTs) developed by ABB Switzerland Ltd., Semiconductors where two anti-parallel high power thyristors are integrated onto one single silicon wafer and are assembled into one housing. This feature enables designers of static VAr compensators, static switches, soft starters and...
متن کاملRational bi-cubic G2 splines for design with basic shapes
The paper develops a rational bi-cubic G2 (curvature continuous) analogue of the non-uniform polynomial C2 cubic B-spline paradigm. These rational splines can exactly reproduce parts of multiple basic shapes, such as cyclides and quadrics, in one by default smoothly-connected structure. The versatility of this new tool for processing exact geometry is illustrated by conceptual design from basic...
متن کاملHyperchaotic behaviour of two bi-directionally coupled Chua's circuits
In this paper, a non-linear bi-directional coupling of two Chua’s circuits is presented. The coupling is obtained by using polynomial functions that are symmetric with respect to the state variables of the two Chua’s circuits. Both a transverse and a tangent system are studied to ensure a global validity of the results in the state space. First, it is shown that the transverse system is an auto...
متن کاملBi-directionally protective communication between neurons and astrocytes under ischemia
The extensive existing knowledge on bi-directional communication between astrocytes and neurons led us to hypothesize that not only ischemia-preconditioned (IP) astrocytes can protect neurons but also IP neurons protect astrocytes from lethal ischemic injury. Here, we demonstrated for the first time that neurons have a significant role in protecting astrocytes from ischemic injury. The cultured...
متن کاملRational design of a cyclin A fluorescent peptide sensor.
We report the design and development of a fluorescent sensor specifically designed to target cyclin A, a protein that plays a key role in the regulation of the cell cycle. Computational studies provide a molecular picture that explains the observed emission increase, suggesting that the 4-DMAP fluorophore in the peptide is protected from the bulk solvent when inserted into the hydrophobic bindi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2014
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.1904